Call us to set up an appointment! 907-747-2726

Sitka Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it attempts to repair itself before the harm was done. Arctic Chiropractic, Sitka is always amazed at what the body can do! Arctic Chiropractic, Sitka sees its Sitka chiropractic care as a partner of the body’s system in healing especially when spine pain is an issue. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to take care of the body. Melatonin is one nutritional tool that is showing value by interrupting the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to its cellular level via autophagy, the natural process during which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a new study, melatonin enhanced autophagy and decreased the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin prevents intervertebral disc degeneration by stimulating autophagy. (3) Wow. Arctic Chiropractic, Sitka is encouraged by this research to see just how well melatonin can work for Sitka back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is quite a common malady seen at Arctic Chiropractic, Sitka that positive news of melatonin’s benefits are quite exciting. A new study described that melatonin could modify the extracellular matrix of the disc remodeling process started by IL-1 β. Further, melatonin decreased the inflammatory cell collection and reduced the release of connected inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin interrupted the IL-1B feedback loop, researchers suggested that melatonin may contribute to the healing process of intervertebral discs after damage was already present. (1) Arctic Chiropractic, Sitka will keep following the new research on the role inflammation performs in Sitka disc degeneration and melatonin’s role in combatting it.

INFLAMMATION AND MELATONIN

The importance of melatonin in helping to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other mechanisms is quite apropos. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by hindering the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin influences the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) activities. (1) Melatonin’s specific influence on inflammation and disc degeneration is most attention-getting to Arctic Chiropractic, Sitka and our Sitka back pain patients.

CONTACT Arctic Chiropractic, Sitka

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she illustrates how The Cox® Technic System of Spinal Pain Management handles disc degeneration for relief of chronic low back pain in her patient.

Schedule your Sitka chiropractic appointment with Arctic Chiropractic, Sitka now. We can talk about how inflammation affects your back pain and how melatonin may help with the related disc degeneration.

 
Arctic Chiropractic, Sitka presents new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
« View All Nutrition Articles
"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."